Exp. Biol. Med. Experimental Biology and Medicine Exp. Biol. Med. 1535-3699 Frontiers Media S.A. 10275 10.3389/ebm.2024.10275 Experimental Biology and Medicine Retraction Retraction: MicroRNA-34a alleviates steroid-induced avascular necrosis of femoral head by targeting Tgif2 through OPG/RANK/RANKL signaling pathway EBM Editorial Office 10.3389/ebm.2024.10275 EBM Editorial Office * *Correspondence: EBM Editorial Office, ebm@ebm-journal.org 25 06 2024 2024 249 10275 06 06 2024 07 06 2024 Copyright © 2024 EBM Editorial Office. 2024 EBM Editorial Office

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 A Retraction of the Original Research Article MicroRNA-34a alleviates steroid-induced avascular necrosis of femoral head by targeting Tgif2 through OPG/RANK/RANKL signaling pathway by Peng W. X., Ye C., Dong W. T., Yang L. L., Wang C. Q., Wei Z. A., Wu J. H., Li Q., Deng J., and Zhang J. (2017). Experimental Biology and Medicine. 242(12):1234–1243. doi: 10.1177/1535370217703975

Following publication, the authors contacted the Editorial Office to request the retraction of the cited article, stating that concerns were raised on the PubPeer platform regarding the reuse of certain images, as well as concerns over incomplete data. Particularly, in Figure 3, Panels c and d appear to overlap. Those panels also show duplication with Figure 11B from Zhang et al 2017 and Figure 5 from Yu et al 2019 (both retracted sources). Further, in Tables 2, 3 values are shown as means ± standard deviation and no exact measurements are provided. Therefore, the article has been retracted.

Comparison of the morphology changes in the femoral head by HE staining among (×100) among normal control, model control, negative control, miR-34a mimics and miR-34a inhibitor groups. (A), normal control group; (B), model control group; (C), negative control group; (D), miR-34a mimics group; (E), miR-34a inhibitors group; miR-34a, miRNA-34a. (A color version of this figure is available in the online journal).

Comparison of parameters of trabecular in the cancellous bone within the unit volume of the center of the femoral head between normal control group and model control group.

Group BV/TV BS/BV Tb.Th Tb.N
Normal control group 0.72 ± 0.07 25.07 ± 2.52 0.14 ± 0.02 6.34 ± 0.63
model control group 0.59 ± 0.06 a 21.25 ± 2.10 a 0.13 ± 0.01 5.83 ± 0.58 a

Compared with the normal control group, p < 0.05; BV/TV, bone volume/total volume. BS/BV, bone surface area/bone volume; Tb.Th, trabecular thickness; Tb.N, trabecular number.

Comparison of parameters of trabecular in the cancellous bone within the unit volume of the center of the femoral head among normal control, model control, negative control, miR-34a mimics and miR-34a inhibitor groups.

Group BV/TV BS/BV Tb.Th Tb.N
Normal control 0.71 ± 0.07 24.92 ± 2.51 0.14 ± 0.03 7.02 ± 0.69
Model control 0.55 ± 0.05 a 20.13 ± 2.01 a 0.13 ± 0.02 5.65 ± 0.56 a
Negative control 0.52 + 0.05 a 20.07 ± 2.00 a 0.13 ± 0.02 5.63 ± 0.56 a
miR-34a inhibitor 0.46 ± 0.04 a , b 17.75 ± 1.75 a , b 0.15 ± 0.04 5.00 ± 0.51 a , b
miR-34a mimics 0.63 ± 0.06 a , b 22.39 ± 2.22 a , b 0.14 ± 0.02 6.39 + 0.63 a , b

Compared to normal control group, p < 0.05.

Compared to model control group, p < 0.05. BV/TV, bone volume/total volume; BS/BV, bone surface area/bone volume; Tb.Th, trabecular thickness; Tb.N, trabecular number.

Figure 3 appears to show an overlap between panels (c) and (d).

Tables 2, 3 show values as means +/− deviation, no exact measurements provided.

This retraction was approved by the Editor-in-Chief of Experimental Biology and Medicine. The authors received communication regarding the retraction but did not respond. The communication has been recorded by the publisher.