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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Exp. Biol. Med.</journal-id>
<journal-title>Experimental Biology and Medicine</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Exp. Biol. Med.</abbrev-journal-title>
<issn pub-type="epub">1535-3699</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">10605</article-id>
<article-id pub-id-type="doi">10.3389/ebm.2025.10605</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Experimental Biology and Medicine</subject>
<subj-group>
<subject>Retraction</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Retraction: Hydrogen-rich saline protects myocardium against ischemia/reperfusion injury in rats</article-title>
<alt-title alt-title-type="left-running-head">EBM Editorial Office</alt-title>
<alt-title alt-title-type="right-running-head">
<ext-link ext-link-type="uri" xlink:href="https://doi.org/10.3389/ebm.2025.10605">10.3389/ebm.2025.10605</ext-link>
</alt-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<collab>EBM Editorial Office</collab>
<xref ref-type="corresp" rid="c001">&#x2a;</xref>
<uri xlink:href="https://loop.frontiersin.org/people/2389573/overview"/>
</contrib>
</contrib-group>
<author-notes>
<corresp id="c001">&#x2a;Correspondence: EBM Editorial Office, <email>ebm@ebm-journal.org</email>
</corresp>
</author-notes>
<pub-date pub-type="epub">
<day>10</day>
<month>04</month>
<year>2025</year>
</pub-date>
<pub-date pub-type="collection">
<year>2025</year>
</pub-date>
<volume>250</volume>
<elocation-id>10605</elocation-id>
<history>
<date date-type="received">
<day>28</day>
<month>03</month>
<year>2025</year>
</date>
<date date-type="accepted">
<day>02</day>
<month>04</month>
<year>2025</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#xa9; 2025 EBM Editorial Office.</copyright-statement>
<copyright-year>2025</copyright-year>
<copyright-holder>EBM Editorial Office</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/">
<p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p>
</license>
</permissions>
<related-article id="RA1" related-article-type="retracted-article" journal-id="Exp. Biol. Med." journal-id-type="nlm-ta" xlink:href="10.3181/0812-RM-349" ext-link-type="doi">A Retraction of the Original Research Article <article-title>Hydrogen-rich saline protects myocardium against ischemia/reperfusion injury in rats</article-title> by Sun Q, Kang Z, Cai J, Liu W, Liu Y, Zhang JH, Denoble PJ, Tao H and Sun X (2009). Experimental Biology and Medicine. 234(10):1212&#x2013;9. doi: <object-id>10.3181/0812-RM-349</object-id>
</related-article>
</article-meta>
</front>
<body>
<p>Following publication, concerns were raised on the <ext-link ext-link-type="uri" xlink:href="http://pubpeer.com/publications/6B5F7DE5DFE1EF80A4DA65694478EE?utm_source=Chrome&#x26;utm_medium=BrowserExtension&#x26;utm_campaign=Chrome">PubPeer platform</ext-link> regarding the integrity of the images in the published figures. Specifically, highlighted sections of the Sham and H2 images in <xref ref-type="fig" rid="F6">Figure 6</xref> appear to be duplicated.</p>
<fig id="F6" position="float">
<label>FIGURE 6</label>
<caption>
<p>Detection of apoptotic cell death by TUNEL staining in the Sham, Control, and H2 groups at the end of 24&#xa0;h of reperfusion. Relative to the Control group, H2 significantly reduced the number of TUNEL-positive cells (blue staining). Values are mean &#xb1; SEM; P &#x3c; 0.01 compared to Control group, n &#x3d; 6 for each group.</p>
</caption>
<graphic xlink:href="ebm-250-10605-g006.tif"/>
</fig>
<p>The authors remained unresponsive and failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Experimental Biology and Medicine&#x2019;s policies. As a result, the data and conclusions of the article have been deemed unreliable, and the article has been retracted.</p>
<p>This retraction was approved by the Editor-in-Chief of Experimental Biology and Medicine. The authors received communication regarding the retraction. EBM would like to thank the users on PubPeer for bringing the published article to our attention.</p>
</body>
</article>