AUTHOR=Burakova Inna , Smirnova Yuliya , Morozova Polina , Pogorelova Svetlana , Kryukova Olga , Kislova Tatiana , Korneeva Olga , Syromyatnikov Mikhail 
  
TITLE=The effect of short-term consumption of Bifidobacterium bifidum on the gut microbiome of obese individuals
  
JOURNAL=Experimental Biology and Medicine
  
VOLUME=Volume 251 - 2026
  
YEAR=2026
  
URL=https://www.ebm-journal.org/journals/experimental-biology-and-medicine/articles/10.3389/ebm.2026.10894
  
DOI=10.3389/ebm.2026.10894
  
ISSN=1535-3699
  
ABSTRACT=It is known that gut microbiota dysbiosis can lead to obesity by disrupting energy consumption and metabolism. Probiotic supplements are a potential therapeutic option for improving intestinal homeostasis. The aim of this study was to investigate the effect of a probiotic supplement containing Bifidobacterium bifidum on the intestinal microbiome of people with obesity using high-throughput sequencing on the DNBSEQ-G50 platform. The study demonstrated a positive effect of the supplement on bacterial species such as Bacteroides uniformis, Alistipes putredinis, Alistipes shahii, Dysosmobacter welbionis, and Gemmiger formicilis. Therefore, we suggest the potential use of this bacterial species in the treatment of gut microbiota dysbiosis of obese individuals.